Hepatic steatosis responsible for 20% of liver cancers, cases of cirrhosis: IGP doctors

ChandigarhAbout 20% of patients with liver cancer or cirrhosis of the liver develop these conditions due to non-alcoholic fatty liver disease (NAFLD) that was left untreated at first, doctors at the Chandigarh said on Thursday. Post Graduate Institute of Medical Education and Research (PGIMER).

Doctors were speaking at an event to mark International Nash (Non-Alcoholic Steatohepatitis) Day. Nash is due to non-alcoholic fatty liver disease, which is also responsible for inflammation (swelling) and scarring (fibrosis).

The overall prevalence of NAFLD in the general population is close to 40%, but the percentage in Chandigarh and Punjab is much higher. On average, PGIMER registers about 60 new cases of NAFLD each week, and cases are expected to increase by 10% over the next two years, the doctors said.

“NAFLD is mainly due to metabolic risk factors related to sedentary lifestyle and high caloric intake. Overweight, obesity, diabetes, hypertension and dyslipidemia are the main risk factors for NAFLD, although some patients may be genetically predisposed In addition to affecting the liver, NAFLD is a common risk factor for different extra-hepatic diseases (cardiovascular disease, chronic kidney disease, bone loss, obstructive sleep apnea and cancers of different organs),” said Ajay Duseja, Professor, Department of Hepatology, PGIMER, and Secretary General, Indian National Association for the Study of the Liver (INASL).

PGIMER in association with INASL, NAFLD Task Force and Indian NAFLD Consortium (ICON-D) have launched an action plan for the prevention and control of Non-Alcoholic Fatty Liver Disease (NAFLD) in India . Experts say mass awareness and sensitization activities are needed to raise people’s awareness of liver disease, and the severity of fatty liver should be stratified for each patient.

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