Human Liver Models Market Size ($ 508.26 million by 2028)

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New York, October 22, 2021 (GLOBE NEWSWIRE) – The new research study on the Human Liver Models Market Size and forecasts to 2028 by type (hepatic organoids, liver on chip, 2D models, 3D bioprinting and others), application (drug discovery, education and others) and end user (pharmaceutical and biotechnology companies, research institutes, and others) with the COVID-19 pandemic impact assessment and global analysis available at https://www.theinsightpartners.com/covid-analysis-sample/TIPRE00025128

Human Liver Models Market: Competitive Landscape and Key Developments
THERMO FISHER SCIENTIFIQUE INC .; Emulate, Inc .; CN Bio Innovations; BIOMEDICAL CYFUSE KK; MIMETAS BV; InSphero; BioIVT; CELLINK; Kerafast; Cyprus; Kirkstall; and ORGANOVO HOLDINGS INC. are among the key companies operating in the human liver models market. The main players are focused on launching new products, expanding and diversifying their market presence, and acquiring new customers to exploit existing business opportunities.

In October 2021, BioIVT launched its HEPATOMUNE kit, a long-term stable in vitro model for evaluating liver damage related to the immune system and inflammation.

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In July 2021, CN Bio and Lonza announced a distribution agreement providing pre-validated hepatocytes for use on an innovative range of organs on a chip.

In 2021, North America dominated the global human liver models market. The growth of the market is largely attributed to the increasing incidence of liver diseases such as cirrhosis, chronic liver disease (CLD), non-alcoholic fatty liver disease (NAFLD) and others across the country. According to the Centers for Disease Control and Prevention (CDC), approximately 21,000 men and 8,000 women in the United States are diagnosed with liver cancer each year, and approximately 16,000 men and 8,000 women die from the disease. In addition, the United States is ahead in technology and R&D activities, which should have a positive impact on the market. For example, in July 2021, InSphero AG announced a breakthrough in 3D cell technology for drug discovery and safety testing with the launch of its 3D human liver disease discovery platform InSight.

Based on type, the human liver models market is segmented into hepatic organoids, liver on a chip, 2D models, 3D bioprinting, and others. The liver organoids segment is the largest shareholder in the market; however, the liver-on-chip segment is expected to register the highest CAGR during the forecast period. By Application, the human liver models market is segmented into education, drug discovery, and others. The drug discovery segment holds the largest share of the human liver models market; however, the educational segment is expected to register the highest CAGR during the forecast period. By end user, the human liver models market is segmented into research institutes, pharmaceutical and biotechnology companies, and others. The pharmaceutical and biotechnology segment is the main shareholder in the market. The research institutes segment is expected to register the highest CAGR in the market during the forecast period.

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There has been an increase in the number of animals used in research along with the increase in research and development in the medical industry. These animals are required in large numbers in preclinical tests. The pain, distress, and death of animals in science experiments has long been a topic of discussion. Several cases show that animal models cannot always predict the body’s response to drugs, especially in drug toxicology studies. This is because the metabolism of drugs and toxins in humans differs considerably from that in animals, making it almost impossible to study drug metabolism in experimental models such as laboratory rodent species. The field of alternative research has accelerated over the past 30 years. In addition, several regulations have been introduced in recent years that restrict the use of animals in research activities around the world. Likewise, several organizations such as Cruelty-Free International and the Fund for the Replacement of Animals in Medical Experiments reject animal models for research purposes. With the advent of three-dimensional (3D) cell culture for making organoids, more relevant human organoid models are being explored to provide safe and effective drug testing, thus minimizing the need for animal testing.

Human Liver Models Market: Segment Overview
The liver-on-a-chip segment is expected to register the highest CAGR in the human liver models market, by type, during the forecast period.

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Key Questions To Ask For Human Liver Models Market:

  • What are the driving factors behind the Human Liver Models Market across the globe?
  • What are the developments led by the major players in the human liver models market?
  • Which region is dominated by the human liver models market?
  • Which segment is growing at the highest CAGR in the human liver models market?
  • Which region is experiencing the fastest growing human liver models market?

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