Kissing can spread norovirus; Mood related to bowel preparation symptoms; Anti-TNF & Psoriasis

NIH scientists have found that enteric viruses such as norovirus and rotavirus can replicate and spread through saliva, making talking, coughing, sneezing and kissing potential routes of transmission. (Nature)

According to the latest count, 320 US cases of acute hepatitis of unknown etiology in children are being investigated by the CDC.

But no common exposure has been identified for unusual cases, with adenovirus detected in 45% of children. (Morbidity and Mortality Weekly Report)

The World Health Organization announced updated guidelines on the treatment of hepatitis C infection in children and adolescents at the annual meeting of the European Association for the Study of the Liver. Catch up all MedPage todayCoverage of the meeting here.

Newly eligible young Americans may be less likely to undergo the recommended colorectal cancer screening. (Cancer epidemiology, biomarkers and prevention)

Two factors, older age and “good mood”, appeared protective against severe symptoms when preparing the bowel for colonoscopy, while female sex, longer working hours and gastrointestinal symptoms earlier were linked to a higher likelihood of severe symptoms. (Digestive and liver disease)

A signature of 133 genes has successfully predicted the incidence of hepatocellular carcinoma (HCC) in patients with non-alcoholic fatty liver disease over 15 years of observation. (Science Translational Medicine)

No “clinically significant difference” in the risk of HCC has been identified between patients taking entecavir or tenofovir for chronic hepatitis B, according to a meta-analysis. (Open JAMA Network)

And statins were associated with a reduced risk of HCC for patients with end-stage renal disease and chronic viral hepatitis, according to an observational study from South Korea. (Scientific reports)

Heat shock protein 47 could be a biomarker to differentiate between fibrotic and non-fibrotic forms of Crohn’s disease, and could also be a potential therapeutic target. (Scientific reports)

Compared with conventional therapies, tumor necrosis factor inhibitors for inflammatory bowel disease and other immune-mediated conditions have been associated with an increased risk of psoriasis, although the absolute risk is “moderate”, have reported researchers in JAMA Dermatology.

Liver stiffness tests may have another use: predicting how long patients will be hospitalized before heart surgery. (Journal of Cardiothoracic and Vascular Anesthesia)

And the liver stiffness test with transient vibration-controlled elastography (FibroScan) improved the prediction of survival outcomes for patients with primary biliary cholangitis who had no previous cirrhosis-related complications. (Journal of Hepatology)

  • Zaina Hamza is a writer for MedPage Today, covering gastroenterology and infectious diseases. She is based in Chicago.

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